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What is Vasculitis Neuropathy

Vasculitis diseases can affect any organ or tissue, including the peripheral nerves. When vasculitis affects the vasa nervorum, the results are often critical ischemia to peripheral nerves and potentially profound clinical sequelae. Vasculitis neuropathy is usually only one feature of a systemic condition that can involve the skin, lungs, kidneys, and other organs. As an example, the group of vasculitis disorders commonly associated with antineutrophil cytoplasmic antibodies (ANCA) (ie, granulomatosis with polyangiitis, microscopic polyangiitis, and eosinophilic granulomatosis with polyangiitis often cause vasculitis neuropathy. Polyarteritis nodosa (PAN) and mixed cryoglobulinemia are also prone to involve the peripheral nervous system. Consult a doctor for medical advice.

Symptoms

  • Motor dysfunction
  • Numbness
  • Pain
  • Paresthesia
  • Sensory dysfunction
  • Weakness of the muscles in the limbs

Treatment

  • Corticosteroids
  • Immunomodulatory therapies
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