What is Multifocal Motor Neuropathy
MMN (Multifocal Motor Neuropathy) is a rare disorder in which focal areas of multiple motor nerves are attacked by one’s own immune system. Patients with MMN can have other symptoms, including twitching, or small random dimpling of the muscle under the skin which neurologists call fasciculations. Consult a doctor for medical advice.
Symptoms
- Asymmetrical muscle weakness
- Atrophy
- cramping
- Decreased muscle tone
- Feelings of tingling or numbness or pain are not associated with the disorder
- Foot drop
- Involuntary muscle contractions or “twitches” (fasciculations)
- Limited endurance
- Progressive muscle weakness of the arms and legs
- Reduced grip strength of the hands and reduced dexterity of the hands is seen.
- Sometimes absent deep tendon reflexes
- Trouble extending or bending their wrist upward (wrist drop)
- Usually is not any sensory deficits
Treatment
- Azathioprine
- Beta-interferon
- Cyclophosphamide
- Cyclosporine
- Gammagard liquid 10%
- General internists
- Immunologists
- Infliximab
- Intravenous immunoglobulin (IVIg)
- Mycophenolate mofetil
- Neurologists
- Orthopedists
- Physical therapy
- Rituximab
- More research is necessary to determine the long-term safety and effectiveness of these therapies for the treatment of multifocal motor neuropathy
