Home Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

What is Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is an acquired immune-mediated inflammatory disorder of the peripheral nervous system that targets your body’s nerves. Polyneuropathy means several nerves are involved. CIDP often affects both sides of the body. CIDP is caused by an abnormal immune response. CIDP occurs when the immune system attacks the myelin cover of the nerves. CIDP is closely related to Guillain–Barré syndrome and it is considered the chronic counterpart of that acute disease. Consult a doctor for medical advice.

Symptoms

  • There are usually some alterations of sensation causing incoordination, numbness, tingling, or prickling sensations. Some patients only have sensory symptoms and signs but have the typical abnormalities of nerve conduction and respond to treatment as in CIDP in which weakness predominates.

Treatment

  • Treatment for CIDP includes corticosteroids such as prednisone, which may be prescribed alone or in combination with immunosuppressant drugs. Plasmapheresis (plasma exchange) and intravenous immunoglobulin (IVIg) therapy are effective. IVIg may be used even as a first-line therapy.
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