Nerve Injuries and the Fixed Dystonia’s of CRPS
by: Mark S. Cooper, PhD, Department of Biology, University of Washington, Seattle, WA, USA
Type of Submission: Letter to Editor
Running Head: CRPS Fixed Dystonias
Nerve injury is a known precipitant of Complex Regional Pain Syndrome (CRPS). However, is nerve injury a primary cause of CRPS dystonia? In 2009, Oaklander and Fields(1) reviewed peripheral aspects of CRPS, asking whether diverse symptoms of this neuropathic pain disorder are linked to small‐fiber neuropathies. These authors also described a possible role for large‐fiber neuropathies in the etiology of CRPS fixed dystonias. This hypothesis adds a valuable new perspective to one of the most controversial topics in neurology: the fixed dystonias of CRPS.
During, and after, the American Civil War, Dr. Silas Weir Mitchell described both intense burning pain (causalgia) and fixed dystonias in a subset …